In modern pharmaceutical and chemical development, hazardous reactions are often unavoidable pathways to creating breakthrough compounds. These reactions—involving high energy reagents, exothermic processes, pressure-sensitive conditions, or toxic materials—require specialized expertise and infrastructure.

DASHA offers comprehensive capabilities for managing these challenging chemistries:

R&D Scale Capabilities:

• Purpose-built laboratories with reinforced blast shields and ventilation
• Calorimetry and real-time reaction monitoring
• High-pressure reaction vessels (up to 100 bar)
• Cryogenic temperature control systems
• Experience with hazardous chemistries and pyrophoric reagent handling in both batch and continuous flow
• Safety assessment and risk mitigation protocols

Commercial Scale Implementation:

• Explosion-proof manufacturing suites
• Hastelloy and specialized alloy equipment
• Continuous flow processing alternatives
• Dedicated catalyst handling facilities
• Automated control systems for critical parameters
• Regulatory-compliant safety documentation

Don’t compromise your innovation pipeline due to chemistry limitations. Partner with us to transform your most challenging reactions into scalable, safe manufacturing processes that deliver your molecules on time and within specification.