At the heart of every pharmaceutical breakthrough lies meticulous research and development. DASHA’s state-of-the-art R&D facility in ALEAP Industrial Area, Hyderabad is equipped to transform your concepts into commercially viable solutions with precision and expertise. Our infrastructure is designed for seamless collaboration and efficient workflow, enabling rapid development cycles while maintaining the highest quality standards.

Core R&D Process Capabilities

Our comprehensive R&D services transform complex molecules into commercially viable APIs through a systematic approach:

• Route Scouting & Selection: Evaluation of multiple synthetic pathways to identify optimal routes balancing efficiency, cost, and scalability
• Process Chemistry Development: Optimization of reaction parameters, reducing impurities and maximizing yields
• Analytical Method Development: Custom method creation for accurate characterization of intermediates and final products
• Scale-Up Optimization: Seamless transition from milligram to kilogram scale with preserved quality and yield
• Tech Transfer Support: Comprehensive knowledge transfer ensuring manufacturing success

 Advanced Capabilities

• Catalyst Screening & Development: Identification of optimal catalysts for stereoselective reactions
• Flow Chemistry: Continuous processing solutions for hazardous or highly exothermic reactions
• Crystallization Studies: Control of polymorphic forms and particle characteristics
• Impurity Profiling & Control: Identification, characterization, and elimination of process-related impurities
• Stability Studies: Evaluation of drug substance stability under various conditions

Physical Infrastructure

Laboratory Facilities

• Chemistry Labs: Fully equipped synthetic chemistry laboratories with fume hoods, analytical instruments, and safety systems
• cGMP Kilo-Lab Facility: Reactors ranging from 5L to 100L with temperature control from -80°C to +150°C
• Clean Room Environments: Controlled areas for sensitive operations and API handling
• Process Safety Lab: Equipment for thermal hazard testing and reaction calorimetry

Analytical Infrastructure

• Chromatography Systems: HPLC, UPLC, GC, and IC with various detection methods
• Thermal Analysis Tools: DSC, TGA, and particle size analysers
• Stability Chambers: ICH-compliant chambers for long-term, intermediate, and accelerated stability studies

Supporting Infrastructure

• Digital Infrastructure: Electronic lab notebooks, LIMS, document management systems
• Project Management Office: Dedicated spaces for client meetings and project coordination
• Pilot Plant Interface: Systems for effective knowledge transfer to manufacturing
• Quality Control Areas: Dedicated space for QC testing and release
• Sample Storage: Controlled environments for sample retention and stability programs

Partner with our R&D team today and accelerate your development timeline from concept to commercialisation!